Antibiotics are key to treating infections in humans and animals – there are no alternatives to treating life-threatening bacterial infections. The world has recognized that antimicrobial resistance (AMR) in humans is a challenge that costs lives. Our vision is a world where veterinary antibiotics are used responsibly to protect and treat animals, and where they maintain their value as a therapeutic tool. An equally important challenge is maintaining and increasing food safety and security. To address these interconnected challenges, companies and organizations commit to five principles and practical actions, and will proactively encourage others to embrace them.